The event now feels like equal parts wildlife management effort, local tradition, and surreal endurance test.

Here's what we know about the 2026 Florida Python Challenge, how the yearly hunt works and a little bit about last year's winner.

Pythons are spreading north in Florida, adapting to cold by using burrows. Scientists warn Brevard County is at risk.

Are Florida's invasive Burmese pythons are more active in warmer months? Signs show signs of cold tolerance, potentially ...

Florida scientists are using opossums to secretly track invasive Burmese pythons in the Everglades-and it's working.

A python hunter captured the second heaviest Burmese python on record in Florida, weighing 202 pounds. The captured female python measured 16 feet, 10 inches long and was found in the Big Cypress ...

Scientists in Florida have launched a new offensive against the Burmese python invasion, this time using opossums, one of the ...

Heightened gator risk: May and June mark alligator mating season, when the reptiles become more aggressive, posing dangers to python hunters in South Florida. Predator rivalry: Alligators and pythons ...

Opossums are becoming Florida’s secret weapon against giant invasive pythons—thanks to GPS collars and a wild discovery.

Florida's summer heat is almost here. Will we be seeing more of our scaly invasive neighbors? The Burmese python is a large, nonvenomous constrictor snake that is an invasive species in Florida.